AEEA-AEEA

AEEA-AEEA (Aminoethoxyethoxyacetate dimer)

Gusaba Ubushakashatsi:
AEEA-AEEA ni hydrophilique, icyogajuru cyoroshye gikoreshwa mubushakashatsi bwa peptide nubushakashatsi bwibiyobyabwenge. Igizwe nibice bibiri bishingiye kuri Ethylene glycol, bituma iba ingirakamaro mukwiga ingaruka zuburebure bwihuza no guhinduka kumikoranire ya molekile, solubile, nibikorwa byibinyabuzima. Abashakashatsi bakunze gukoresha ibice bya AEEA kugirango basuzume uburyo icyogajuru kigira ingaruka kumikorere ya antibody-ibiyobyabwenge (ADCs), peptide-ibiyobyabwenge, nibindi bioconjugate.

Imikorere:
AEEA-AEEA ikora nkibinyabuzima bihuza byongera imbaraga zo gukemura, bigabanya inzitizi zidasanzwe, kandi bigahindura imikorere ya molekile. Ifasha gutandukanya domaine ikora muri molekile, nko kwibasira ligande hamwe nu mutwaro, byemerera guhuza ibikorwa neza. Imiterere yacyo idafite ubudahangarwa na hydrophilique nayo igira uruhare mugutezimbere imiti ya farumasi ikoreshwa muburyo bwo kuvura.