Melanotan II

Melanotan II API

Melanotan IIni synthique cyclic heptapeptide igereranya yaα-melanocyte-itera imisemburo (α-MSH), yateye imbere kurigukangura melanogenez, kuzamuraKurinda UV, no kwiganaimikorere yimibonano mpuzabitsina. Ikora nka akudatoranya agonistya reseptor ya melanocortin, cyaneMC1R, MC3R, naMC4R.

Ubanza yize kubwayokumanikanagufotoraimitungo, Melanotan II nayo yerekanye ingaruka kurikuzamura libido, guhagarika ubushake bwo kurya, nakuringaniza ingufu, kuyigira peptide yubushakashatsi ikora kandi ishishikajwe na dermatology, endocrinology, nubuvuzi bwimibonano mpuzabitsina.

Uburyo bwibikorwa

Melanotan II ikora mugukora reseptor nyinshi za melanocortin:

• MC1R: Ikanguraumusaruro wa melanin→ byongera pigmentation yuruhu no kurinda UV

• MC3R / MC4R: Uruharekurwanya ubushake bwo kurya, kuzamura libido, naingufu homeostasis

• Kurenga inzitizi yubwonko bwamaraso, bigira ingaruka hagati ya neurohormonal inzira

Ubushakashatsi nibishoboka

Nubwo bitemewe gukoreshwa mubuvuzi, Melanotan II yizwe cyane kubikurikira:

1. Uruhu Pigmentation & Kurinda UV

• Guteza imbereeumelanin synthesis, Kurigutwika bisanzwe

• Itangaingaruka zo gukingiranta zuba

• Ibishobora kugabanya kanseri y'uruhu kubantu bafite uruhu rwiza

2. Imikorere mibi yimibonano mpuzabitsina

• Yerekanwa kuriongera libido no kubyutsa igitsinahaba mu bagabo no mu bagore

• Yize nkibishobora kuvurwa kurikudakora neza (ED)ukoresheje MC4R

3. Kurya no Kuringaniza Ibiro

• Gicurasigabanya ubushake bwo kurya no gufata ibiryomukora kuri hypothalamic inzira

• Ibishoboka byongeweho muriubushakashatsi bw'umubyibuho ukabije

Ibiranga API (by Itsinda rya Gentolex)

• Isuku ryinshi ≥ 99%(HPLC & LC-MS byemejwe)

• Gukomatanya binyuzesynthesis ikomeye ya peptide (SPPS)

• Endotoxine nkeya, ibisigara bike bisigaye

• BirashobokaR&D kurwego rwubucuruzi