Retatrutide numuti wambere wiperereza ugereranya igisekuru gishya cyo gucunga ibiro hamwe nubuvuzi bwa metabolike. Bitandukanye n'imiti gakondo yibasira inzira imwe, Retatrutide niyambere ya gatatu agonist ikora GIP (glucose-iterwa na insulineotropique polypeptide), GLP-1 (glucagon isa na peptide-1), hamwe na reseptor ya glucagon icyarimwe. Ubu buryo budasanzwe butuma butanga ingaruka zikomeye zo kugabanya ibiro, gucunga glucose yamaraso, nubuzima bwa metabolike.
Uburyo Retatrutide ikora
1. Ikora GIP yakira
- Kongera imisemburo ya insuline mugusubiza ibiryo.
- Kunoza imikorere ya metabolike no gukoresha ingufu.
- Agira uruhare rutaziguye mu kugabanya ibinure no kunoza insuline.
2. Bitera GLP-1 Kwakira
- Itinda gusiba gastric, igufasha kuguma wuzuye igihe kirekire.
- Kurwanya ubushake no kugabanya kalori muri rusange.
- Itezimbere isukari yamaraso mukongera insuline no kugabanya glucagon.
3. Yinjiza Glucagon
- Yongera ingufu zikoreshwa mugutezimbere thermogenezesi (gutwika amavuta).
- Ifasha guhindura umubiri mububiko bwamavuta ukajya gukoresha amavuta.
- Shyigikira kugabanya ibiro birebire mukuzamura igipimo cya metabolike.
- Gukomatanya Ibice bitatu-Ibikorwa
Muguhitamo reseptors zose uko ari eshatu, Retatrutide icyarimwe:
- Kugabanya gufata ibiryo
- Yongera guhaga
- Yongera ibinure
- Kunoza igenzura rya glycemic
Ubu buryo butatu-butanga imisemburo butuma habaho imbaraga zikomeye kuruta GLP-1 cyangwa agoniste ebyiri yonyine.
Bifata igihe kingana iki kugirango ubone ibisubizo?
Igeragezwa rya Clinical ryerekanye umusaruro wihuse kandi wingenzi:
| Igihe ntarengwa | Ibisubizo Byarebwaga |
|---|---|
| Ibyumweru 4 | Kugabanya ubushake bwo kurya, kunoza guhaga, kugabanya ibiro hakiri kare |
| Ibyumweru 8-12 | Kugaragara kw'ibinure, kugabanuka kuzenguruka mu kibuno, kuzamura ingufu |
| Amezi 3-6 | Kugabanya ibiro bikomeye kandi bihamye, kugenzura neza isukari mu maraso |
| Umwaka 1 (ibyumweru 72) | Kugeza kuriKugabanya ibiro 24-26%mu matsinda menshi |
Gutezimbere hakiri kare
Abenshi mu bitabiriye amahugurwa bavuga ko ubushake bwo kurya no guhindura ibiro byambere mu byumweru 2-4.
Gutakaza Ibiro Bikomeye
Ibisubizo byingenzi bigaragara mubisanzwe amezi 3, bikomeza mugihe cyumwaka 1 hamwe no gukoresha neza no kunywa neza.
Impamvu Retatrutide ifatwa nk'intambwe
- Gukoresha inshuro eshatu kwakirwa bitandukanya nubuvuzi bugezweho.
- Kugabanya ibiro birenze urugero ugereranije na GLP-1 cyangwa imiti ibiri ya agonist.
- Itezimbere ubuzima bwa metabolike hamwe nibigize umubiri, kugabanya ibinure mugihe urinda imitsi.
Umwanzuro
Retatrutide itangiza uburyo bushya bwo gucunga ibiro ukoresheje imisemburo karemano yumubiri. Binyuze mubikorwa bitatu bya agonist, bigabanya ubushake bwo kurya, byongera metabolisme, kandi byongera cyane gutakaza amavuta. Mugihe iterambere ryambere rishobora kugaragara mukwezi kwa mbere, ibisubizo bihinduka cyane bigenda bitera imbere mugihe cyamezi menshi - bigatuma Retatrutide imwe mumiti itanga icyizere cyumubyibuho ukabije nindwara ziterwa na metabolike mugihe cya vuba.
Igihe cyo kohereza: Ukwakira-28-2025