Mu myaka yashize, GLP-1 yakira reseptor agoniste yagutse byihuse kuva mubuvuzi bwa diyabete igera kubikoresho byingenzi byo gucunga ibiro, iba imwe mumirenge ikurikiranwa cyane muri farumasi yisi. Kuva hagati ya 2025, iyi mbaraga yerekana nta kimenyetso cyo gutinda. Ibihangange mu nganda Eli Lilly na Novo Nordisk bitabira amarushanwa akomeye, amasosiyete ya farumasi y’Abashinwa araguka ku rwego mpuzamahanga, kandi intego nshya n’ibimenyetso bikomeje kugaragara. GLP-1 ntikiri icyiciro cyibiyobyabwenge gusa - igenda ihinduka urubuga rwuzuye rwo gucunga indwara ziterwa na metabolike.
Tirzepatide ya Eli Lilly yatanze umusaruro ushimishije mu manza nini zo mu mavuriro y’umutima n’imiyoboro y’imitsi, ntizigaragaza gusa ingaruka nziza mu isukari mu maraso no kugabanya ibiro, ahubwo inarinda umutima n’amaraso. Indorerezi nyinshi mu nganda zibona ko ari intangiriro y '“umurongo wa kabiri wo gukura” ku buvuzi bwa GLP-1. Hagati aho, Novo Nordisk ihura n’ibibazo - kugabanya ibicuruzwa, kugabanuka kwinjiza, no guhindura ubuyobozi. Amarushanwa mu mwanya wa GLP-1 yavuye ku “ntambara yo guhagarika” yerekeza ku isiganwa ry’ibinyabuzima ryuzuye.
Kurenga inshinge, umuyoboro uratandukanye. Amagambo yo mu kanwa, molekile ntoya, hamwe nubuvuzi buvanze biri gutezwa imbere n’amasosiyete atandukanye, byose bigamije kunoza iyubahirizwa ry’abarwayi no kwigaragaza ku isoko ryuzuye. Muri icyo gihe, uruganda rukora imiti mu Bushinwa rwumva rucecetse, rukabona amasezerano mpuzamahanga y’impushya zifite agaciro ka miliyari y’amadolari - kikaba ari ikimenyetso cy’uko Ubushinwa buzamuka mu iterambere ry’ibiyobyabwenge.
Icy'ingenzi cyane, imiti ya GLP-1 irenze umubyibuho ukabije na diyabete. Indwara z'umutima n'imitsi, indwara y’umwijima idafite inzoga (NAFLD), indwara ya Alzheimer, ibiyobyabwenge, ndetse n’ibitotsi, ubu hakomeje gukorwa iperereza, hakaba ibimenyetso byinshi byerekana ko GLP-1 ishobora kuvura muri utwo turere. Mugihe ibyinshi muribi bikorwa bikiri mubyiciro byubuvuzi, bikurura ishoramari ryubushakashatsi ninyungu zishoramari.
Ariko, kwiyongera kwa GLP-1 kuvura nabyo bizana impungenge z'umutekano. Raporo iheruka ihuza igihe kirekire GLP-1 ikoreshwa nibibazo by amenyo hamwe nuburwayi budasanzwe bwa optique yazamuye amabendera atukura haba mubaturage ndetse nababishinzwe. Kuringaniza imikorere n'umutekano bizaba ingenzi mu kuzamura inganda zirambye.
Ibintu byose byasuzumwe, GLP-1 ntikiri uburyo bwo kuvura gusa - yahindutse ikibuga cyintambara hagati mumarushanwa yo gusobanura ejo hazaza h'ubuzima bwa metabolike. Kuva mu guhanga siyanse kugeza guhungabana ku isoko, kuva muburyo bushya bwo gutanga kugeza ku ndwara zagutse, GLP-1 ntabwo ari ibiyobyabwenge gusa - ni amahirwe yo kubyara.
Igihe cyo kohereza: Kanama-01-2025