Pregabalin yo kuvura periferi Neagiyeria no gufata ingenzi mu gufatanya igice cyafashwe igice
Ibisobanuro birambuye
| Izina | Pregabalin |
| Umubare wa Cas | 148553-50-8-8-8-8 |
| Formulala | C8h17No2 |
| Uburemere bwa molekile | 159.23 |
| Umubare wa EINECS | 604-639-1 |
| Ingingo itetse | 274.0 ± 23.0 ° c |
| Ubuziranenge | 98% |
| Ububiko | Bifunze mu bushyuhe bwumutse, icyumba ubushyuhe |
| Ifishi | Ifu |
| Ibara | Cyera |
| Gupakira | Pe Umufuka + Umufuka wa Aluminium |
Synonyme
3 (s) - (aminomethyl) -5-methylhexanoic aside; aside; prednisolonediupesphosphashas; (r) -pregalin; (s) -prindalin
Ingaruka ya farumasi
Ingaruka ya farumasi
Pregabalin ifite ingaruka nziza yo kuvura kuri epilepsy. Ubushakashatsi ku moderi zitandukanye z'inyamaswa za epileptique zerekanye ko Preegabalin ishobora gukumira cyane igicuri, kandi igipimo cyacyo gifite inshuro 3-10 munsi ya Gabapentin. Ubushakashatsi bwabonye ko Preegabalin ishobora kugabanya imiyoboro ya serivise na moteri ya moteri, kugabanya imyitwarire ijyanye na diyabete ya viebete na diabete cyangwa imiti ya chiphera cyangwa kugabanya ububabare bushingiye ku bubabare buterwa na stimpuli. imyitwarire ya. Ubushakashatsi bwinyamaswa bwabonye ko Preegabalin ishobora kugira inyungu zifatanije na OpioIids. Pregabalin itanga uburyo bushya bwo kuvura ubuvuzi bwa neuropathic.
Uburyo
Pregabalin irashobora kugabanya kurekura calcium ya SturingsmitTmitsters zimwe na zimwe umuyoboro wa Calcium. Nubwo Pregabalin ari ko bakomoka kuri inebivory neurotranctritter γ-aminobutyric acide. Ntabwo bihindura Gaba gutesha agaciro. However, the study found that prolonged exposure of cultured neurons to pregabalin increased the density of GABA transporters and the rate of functional GABA transport. Pregabalin ntabwo abuza imiyoboro ya sodium, nta gikorwa na kimwe cyakira abashyitsi, ntabwo ihindura ibikorwa bya dopamine na serotonin, kandi ntibibuza reactivation ya Dopamine, Serotonine, cyangwa Norepinephrine. kugenda.
Imikoranire yubuvuzi
1. Ntabwo ari abantu na sisitemu ya C450 rero, ntibikunze gukorana nibindi biyobyabwenge. Ntabwo bigira ingaruka kuri farumacotique yibiyobyabwenge bya antieptileptic (nka sodium firprote, phenytoin, lamotrigine, penobarbital, tornobar
2. Iyo iki gicuruzwa gikoreshwa hamwe na oxycodone, imikorere yacyo izagabanuka kandi ibyangiritse bya moteri bizakurwa.
3. Ifite ingaruka zo kongeramo na lorazepam na ethanol.
