Ibicuruzwa
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CJC-1295
C.
Ibiranga ibicuruzwa:Isuku ≥ 99%
Umuyoboro muke usigaye hamwe nicyuma kiremereye
Endotoxine-yubusa, inzira ya synthesis idafite immunogenic
Ingano yihariye: mg kugeza kg
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NAD +
Ibiranga API:
Isuku ryinshi ≥99%
Urwego rwa farumasi NAD +
GMP isa ninganda zikora
NAD + API nibyiza gukoreshwa mubitunga umubiri, inshinge, hamwe nubuvuzi bwa metabolike.
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Boc-Tyr (tBu) -Aib-Glu (OtBu) -Gly-OH
Boc-Tyr (tBu) -Aib-Glu (OtBu) -Gly-OHni tetrapeptide ikingiwe ikoreshwa mubushakashatsi bwa peptide. Amatsinda ya Boc (tert-butyloxycarbonyl) na tBu (tert-butyl) akora nk'amatsinda arinda amatsinda kugirango akumire ingaruka mugihe cyo guteranya urunigi rwa peptide. Kwinjizamo Aib (α-aminoisobutyric aside) bifasha gutera ibyubaka no kongera peptide itajegajega. Uru ruhererekane rwa peptide rwizwe kubushobozi bwarwo mu isesengura rihuza, gupfunyika peptide, no kuba inyubako yo guteza imbere peptide ya bioaktike ifite imbaraga zihamye kandi zihariye.
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Cagrilintide
Cagrilintide ni syntetique, ikora amylin reseptor agonist ikora igihe kirekire kugirango ivure umubyibuho ukabije hamwe nuburwayi bwa metabolike. Mu kwigana imisemburo isanzwe amylin, ifasha kugenzura ubushake bwo kurya, gutinda kwa gastrica, no kongera guhaga. Isuku yacu-Cagrilintide API ikorwa hifashishijwe synthesis ya chimique kandi yujuje ubuziranenge bwa farumasi, bigatuma ikoreshwa muburyo bwo gucunga neza ibiro.
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Tesamorelin
Tesamorelin API ikoresha tekinoroji ikomeye ya peptide synthesis (SPPS) kandi ifite ibintu bikurikira:
Isuku ≥99% (HPLC)
Nta endotoxine, ibyuma biremereye, ibishishwa bisigaye byageragejwe
Urutonde rwa aside amine nuburyo byemejwe na LC-MS / NMR
Tanga umusaruro wihariye muri garama kuri kilo -
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH ni dipeptide yubaka ikoreshwa muri synthesis ya peptide ikomeye (SPPS). Ihuza isoleucine irinzwe na Fmoc na Aib (α-aminoisobutyric acide), aside amine idasanzwe karemano yongerera imbaraga za helix no kurwanya protease.
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![Fmoc-L-Lys [Eic (OtBu) -γ-Glu (OtBu) -AEEA-AEEA] -OH](https://cdn.globalso.com/gentolexgroup/Glepaglutide6-300x300.png)
Fmoc-L-Lys [Eic (OtBu) -γ-Glu (OtBu) -AEEA-AEEA] -OH
Fmoc-L-Lys. Igaragaza icyerekezo cya Eic (eicosanoid) kugirango imikoranire ya lipide, γ-Glu igamije, hamwe na AEEA icyogajuru kugirango ihindurwe.
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Boc-Tyr (tBu) -Aib-OH
Boc-Tyr (tBu) -Aib-OH ni inyubako ya dipeptide irinzwe ikoreshwa muri synthesis ya peptide, ihuza tirozine irinzwe na Boc na Aib (α-aminoisobutyric aside). Ibisigisigi bya Aib byongera imiterere ya helix no kurwanya protease.
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Boc-We (Trt) -Ala-Glu (OtBu) -Gly-OH
Boc-His (Trt) -Ala-Glu (OtBu) -Gly-OH ni agace ka tetrapeptide karinzwe gakoreshwa muri synthesis ya peptide ikomeye (SPPS) no guteza imbere imiti ya peptide. Harimo amatsinda arinda synthèse ya orthogonal kandi agaragaza urukurikirane rwingirakamaro muburyo bwa bioactive na peptide yubatswe.
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Fmoc-Lys (Pal-Glu-OtBu) -OH
Fmoc-Lys (Pal-Glu-OtBu) -OH numuyoboro wihariye wa lipide ya amino acide yagenewe peptide - lipid conjugation. Iranga lysine irinzwe na Fmoc hamwe na palmitoyl-glutamate kumurongo wuruhande, byongera membrane isano hamwe na bioavailability.
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Fmoc-We-Aib-OH
Fmoc-His-Aib-OH ni inyubako ya dipeptide ikoreshwa muri synthesis ya peptide, ihuza histidine irinzwe na Fmoc na Aib (acide α-aminoisobutyric). Aib itangiza gukomera, bigatuma igira agaciro mugushushanya peptide ihamye kandi ihamye.
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Boc-We (Trt) -Aib-Glu (OtBu) -Gly-OH
Boc-His (Trt) -Aib-Glu (OtBu) -Gly-OH ni agace ka tetrapeptide karinzwe gakoreshwa muri synthesis ya peptide no guteza imbere ibiyobyabwenge. Irimo amatsinda yimikorere ikingiwe muburyo bwo guhuza intambwe hamwe nibiranga Aib (α-aminoisobutyric aside) kugirango yongere imbaraga za helix hamwe no gukomera.