Hindura T3 kuri synthesis, indaya, umusaruro w'ingufu n'amabwiriza
Ibisobanuro birambuye
| Izina | Hindura T3 |
| Umubare wa Cas | 5817-39-0 |
| Formulala | C15h12i3no4 |
| Uburemere bwa molekile | 650.97 |
| Gushonga | 234-238 ° C. |
| Ingingo itetse | 534.6 ± 50.0 ° C. |
| Ubuziranenge | 98% |
| Ububiko | Komeza ahantu h'umwijima, ufunze mu bwumye, ububiko muri firigo, munsi ya -20 ° C. |
| Ifishi | Ifu |
| Ibara | Pale Beige Kuri Brown |
| Gupakira | Pe Umufuka + Umufuka wa Aluminium |
Synonyme
Gusubiramo 3 (3,3 ', 5'-Indiodo-l-Twerronine); l-tyroxy, O- 3,5 . -icyubahiro (gusubiramo 3) igisubizo
Ingaruka ya farumasi
Ibisobanuro
Glande ya tiroyide ni glande nini cyane mumubiri wumuntu, kandi ibintu bifatika bikora byanze bikunze ni TriomEthronine (T4) nibyingenzi muri synthesis, kugenzura ubushyuhe bwumubiri no gutanga inkunga hamwe nuruhara. Byinshi muri T3 muri Serumu yahinduwe muburyo bworoshye bwa peripheri, kandi igice gito cya T3 kiva mu buryo butaziguye na tiroyide kandi kirekuwe mu maraso. Benshi muri T3 muri Serumu bagengwaga kuri poroteyine, hafi 90% byacyo bikaba bigenewe Albumin. Ibiri muri T3 muri Serumu ni 1/200 / 50 muri T4, ariko ibikorwa bifatika bya t3 ni inshuro 5-10 za t4. T3 ifite uruhare runini mugucira umubiri wumubiri wumuntu, niko bifite akamaro gakomeye kugirango tumenye ibirimo T3 muri Serumu.
Ibisobanuro bya Clinical
Icyemezo cya Indiothyeronine nimwe mubipimo byumvikana kugirango asuzume hyperthyroidism. Iyo hyperthyroidism yiyongereye, nukubanziriza kwisubiraho hyperthIbism. Byongeye kandi, iziyongera mugihe cyo gutwita na hepatite ikaze. Hypothyroidism, goiter yoroshye, nephritis nini kandi idakira, Hepatite idakira, umwijima wa cirrhose wagabanutse. Icyemezo cya Serumu Icyemezo cya T3 gishobora gukoreshwa mugupima T3-Hypertyyroidism, kumenyekanisha hyperthIbism hakiri kare no gusuzuma pseudietiroxisosis. Urwego rwa Serum T3 muri rusange ruhuye nimpinduka za T4. Nicyo kimenyetso cyo gusuzuma imikorere ya tiroyide, cyane cyane kubipima hakiri kare. Nibimenyetso byihariye byo gusobanura kuri T3 hyperthyroidiidism, ariko ifite agaciro gake kubisuzumye byimikorere ya tiroyide. Ku barwayi bavugijwe nibiyobyabwenge bya tiroyide, bigomba guhuzwa na tiroxine yose (TT4) kandi, nibiba ngombwa, thyrotropin (tsh) icyarimwe kugirango ifashe gucira urubanza imikorere ya tiroyide.
