Tianeptine kuri sisitemu 5-ht, disation, anti-acetylcholine na cardiotoxigine kugirango wihebe

Ingaruka ya farumasi

1. Uburyo bwo kudakunda iki gicuruzwa buratandukanye n'icya TCA gakondo TCA. Irashobora kongera uptake ya 5-ht muri cleft ya synaptic, ariko ifite ingaruka zidakomeye kuri couptake ya 5-ht na na. Birashobora kugira ingaruka zo kuzamura 5-HT Neuronal. Ntabwo ifite isano kubakira m, H1, α1 na α2-na resitora.
2. Ibyifuzo bya antidepression byiki gicuruzwa bisa nibya TCA, numutekano wacyo no kwihanganira biruta TCA (antideprepressique ya Tricyclic). Imikorere yiki gicuruzwa isa niya SSri Fluoxetine.
3. Ubushakashatsi bwibiyobyabwenge bwibiyobyabwenge bwerekanye ko bushobora: Ongera ibikorwa byigihe gito byingirabuzimafatizo za pippocampus hanyuma wihutisha gukira mubikorwa byayo nyuma yo kubuza; Ongera reabsorpription ya 5-hydroxytryptamine na neurons muri contex na hippocampus.

Ubushakashatsi bwuburozi

- Ibizamini byuburozi, subacute nibizamini byigihe kirekire: Nta mpinduka muri biologiya, imikorere yumwijima, anatory pathologiya.
- Uburozi bwimyororokere nikizamini cya Teratongano: Tianeptine nta ngaruka igira ku bushobozi bw'imyororokere y'ababyeyi bavuwe no ku rubavu n'urubyaro.
- Ikizamini cya mugwage: Tianeptine ntabwo ifite mutasige.

Ingaruka

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- kudasinzira, gusinzira, kurota, intege nke;
- Tachycardia, inyongeramusi, ububabare buke;
- Kurwana, kubabara umutwe, gucika intege, guhindagurika, bikubita mu maso;
- Guhumeka, kumva ubwinshi mu muhogo;
- Myalgia, ububabare bwinyuma, nibindi