Boc-We (Trt) -Aib-Gln (Trt) -Gly-OH

Boc-We (Trt) -Aib-Gln (Trt) -Gly-OH

Gusaba Ubushakashatsi:
Iyi tetrapeptide ikingiwe ikoreshwa muri peptide synthesis hamwe nubushakashatsi bujyanye. Kwinjizamo Aib (α-aminoisobutyric acide) bituma abashakashatsi bakora iperereza ku miterere ihindagurika ndetse n imyitwarire igabanuka muri peptide ngufi. Amatsinda akingiwe arinzwe (Boc, Trt) yemeza ituze no guhitamo mugihe cya synthesis ya peptide ikomeye, ikaba icyitegererezo cyiza cyo kwiga peptide yumugongo ningaruka zuruhande.

Imikorere:
Boc-His (Trt) -Aib-Gln (Trt) -Gly-OH ikora nk'icyitegererezo cyo gushakisha peptide ihamye hamwe nuburyo bwimiterere. Aib igira uruhare muburyo bwo guhagarara neza, mugihe ibisigisigi bya histidine na glutamine bitanga ibibanza bishobora gukorana, bifite akamaro mugushushanya peptide ya bioactive cyangwa kwigana ibice bya poroteyine. Irashobora kandi kuba intangiriro ya peptide ikora mugutezimbere ibiyobyabwenge cyangwa ibinyabuzima.