Izina | EptifibaTide |
Umubare wa Cas | 188627-80-7 |
Formulala | C35H49N11O9S2 |
Uburemere bwa molekile | 831.96 |
Umubare wa EINECS | 641-366-7 |
Ubucucike | 1.60 ± 0.1 g / cm3 (byahanuwe) |
Imiterere | Yashyizweho ikimenyetso cyumye, ububiko muri firigo, munsi ya -15 ° C. |
EptifibaTideacetalt; eptifibaTide, MPA-Har-Gly-gly-gly-gyp-tr-gly-gly-gly-gly-gly-trprelin; n6- (aminoiimilin; nh- (aminoimi Nomethyl) -n2- (3-mercapto-1-oxopropyl-l-lysylglyyl-l-asptophyl-l-prolyl-l-gysptophyl-l-poltyl-l-gysptophyl-l-ly-gysptophyl-l-ex-asp-gyp-gyp-trp-trp-trpridebridge, MPA1-CSS6).
EtifibaTide (Intepuline) ni polyproptide ya polyprot glycoprotein ib / iii ibuza guterana kwa theoptonist, ibuza guterana kwa theoptonist, ibuza guterana kwa theoptonist, ibuza guterana kwa theoptonist, ibuza guterana kwa thia Ugereranije na monoclonal antibody abciximab, eptifibaTide ifite icyerekezo gikomeye, cyerekezo cya Gpib / III yihariye kubera kubaho kwa Conservaneke Kubwibyo, bigomba kugira ingaruka nziza zumuti mu mvugo zishyize mu gaciro za Syndrome ya Coronary. Platelet GlycoProtein IIB / III yanze imiti igabanya ibyangombwa byateguwe cyane, kandi kuri ubu hari ubwoko 3 bwimyiteguro mpuzamahanga, Abcifibat na Tirofibani. ). Hano hari uburambe buke mugukoresha platelet glycoprotein gpib / iia kwakira abarwanya abatavuga mubushinwa, kandi ibiyobyabwenge birahari nabyo ni bike cyane. Gusa ibiyobyabwenge, hydrochloride ya tirofiban, biri ku isoko. Kubwibyo, hateguwe platile nshya glycoprotein IIB yatejwe imbere. / Iiia reseptor Antagononiste ni ngombwa. Ibicuruzwa byo mu gihugu ni ibicuruzwa byigana byakozwe na Chengdu Sino Ibinyabuzima Coo Ibinyabuzima Cojo, Ltd.
Ibyiciro bya Antiplalet Ibiyobyabwenge
Ibiyobyabwenge bigabanya ibiyobyabwenge birashobora kugabanywa mu byiciro bitatu: 1. Cyclooxyelegisenase-1 (cox-1) ibirimo, nka aspirine. 2. Kubuza igiteranyo cyatewe na Adenosine Diphosphate (ADP), nka Clopidogrel, PrasGupagne, Tirofibab, Eptifibab, Eptifibat, nibindi. Prostaglandin EP3 Reseptor Abagizi ba nabi, bashya ba synthesing ibice bya shimi hamwe nikuramo ryiza mubuvuzi gakondo.