Eptifibatide yo kuvura Syndrome ikaze ya Coronary 188627-80-7
Ibicuruzwa birambuye
| Izina | Eptifibatide |
| Numero ya CAS | 188627-80-7 |
| Inzira ya molekulari | C35H49N11O9S2 |
| Uburemere bwa molekile | 831.96 |
| Umubare wa EINECS | 641-366-7 |
| Ubucucike | 1.60 ± 0.1 g / cm3 (Biteganijwe) |
| Imiterere yo kubika | Ikidodo cyumye, ubike muri firigo, munsi ya -15 ° C. |
Synonyme
Eptifibatideacetatesalt; Eptifibatide, MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2, MPAHARGDWPC-NH2,> 99%; MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2; INTEGRELIN (Eptifibatide; nomethyl) -N2- (3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide; MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2 (CYANE)
Platelet Glycoprotein Antagonist
Etifibatide (integrilin) nigitabo gishya cyitwa polypeptide platelet glycoprotein IIb / IIIa reseptor antagonist, ibuza guteranya platine na trombose muguhagarika inzira yanyuma ihuriweho na platine. Ugereranije na antibody monoclonal abciximab, eptifibatide ifite imbaraga, icyerekezo kandi cyihariye guhuza GPIIb / IIIa bitewe nuko hariho insimburangingo imwe ya aminide acide-lysine yo gusimbuza arginine. Kubwibyo, bigomba kugira ingaruka nziza zo kuvura mugihe cyo kuvura syndrome ya acute coronary. Platelet glycoprotein IIb / IIIa imiti igabanya ubukana bwa antagonist yakozwe cyane, kandi kuri ubu hari ubwoko 3 bwimyiteguro ishobora gukoreshwa mumavuriro mpuzamahanga, abciximab, eptifibatide na tirofiban. ). Hano hari uburambe buke mukoresha platelet glycoprotein GPIIb / IIIa reseptor antagonist mubushinwa, kandi imiti iboneka nayo ni mike cyane. Umuti umwe gusa, tirofiban hydrochloride, uri ku isoko. Kubwibyo, platelet nshya glycoprotein IIb yakozwe. / IIIa reseptor antagonist ni ngombwa. Eptifibatide yo murugo nigicuruzwa cyigana cyakozwe na Chengdu Sino Biologiya Products Co., Ltd.
Ibyiciro
Gutondekanya imiti igabanya ubukana bwa Antiplatelet
Imiti igabanya ubukana bwa antiplatelet irashobora kugabanywamo ibyiciro bitatu: 1. Cyclooxygenase-1 (COX-1) inhibitor, nka aspirine. . bivuye mu buvuzi gakondo bw'Abashinwa.
