Eptifibatide yo kuvura Syndrome ikaze ya Coronary 188627-80-7
Ibisobanuro birambuye
| Izina | Eptifibatide |
| Numero ya CAS | 188627-80-7 |
| Inzira ya molekulari | C35H49N11O9S2 |
| Uburemere bwa molekile | 831.96 |
| Umubare wa EINECS | 641-366-7 |
| Ubucucike | 1.60 ± 0.1 g / cm3 (Biteganijwe) |
| Imiterere yo kubika | Gifunze mu cyumye, ubike muri firigo, munsi ya -15 ° C. |
Synonyme
Eptifibatideacetatesalt; Eptifibatide, MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2, MPAHARGDWPC-NH2,> 99%; MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2; INTEGRELIN; (Aminoiminomethyl) -N2- (3-mercapto -1 (DISULFIDEBRIDGE, MPA1-CYS6).
Platelet Glycoprotein Antagonist
Etifibatide (integrilin) ni agashya ka polypeptide platelet glycoprotein IIb / IIIa reseptor antagonist, ibuza gukusanya platine hamwe na trombose muguhagarika inzira yanyuma ihuriweho na platine.Ugereranije na antibody ya monoclonal abciximab, eptifibatide ifite imbaraga, icyerekezo kandi cyihariye guhuza GPIIb / IIIa bitewe nuko hariho insimburangingo imwe ya aside amine-lysine yo gusimbuza arginine.Kubwibyo, bigomba kugira ingaruka nziza zo kuvura mugihe cyo kuvura syndrome ya acute coronary.Platelet glycoprotein IIb / IIIa reseptor antagonist imiti yateye imbere cyane, kandi kuri ubu hari ubwoko 3 bwimyiteguro ishobora gukoreshwa mumavuriro mpuzamahanga, abciximab, eptifibatide na tirofiban.).Hano hari uburambe buke mukoresha platelet glycoprotein GPIIb / IIIa reseptor antagonistes mubushinwa, kandi imiti iboneka nayo ni mike cyane.Umuti umwe gusa, tirofiban hydrochloride, uri ku isoko.Kubwibyo, platelet nshya glycoprotein IIb yakozwe./ IIIa reseptor antagonist ni ngombwa.Eptifibatide yo murugo ni ibicuruzwa byigana byakozwe na Chengdu Sino Biologiya Products Co., Ltd.
Ibyiciro
Gutondekanya imiti igabanya ubukana
Imiti igabanya ubukana bwa antiplatelet irashobora kugabanywamo ibice bitatu: 1. Cyclooxygenase-1 (COX-1) inhibitor, nka aspirine.2. Kubuza gukusanya platelet iterwa na adenosine diphosphate (ADP), nka clopidogrel, prasugrel, cangrelor, ticagrelor, nibindi 3. Platelet glycoprotein Ⅱb / Ⅲa reseptor antagonistes, nka abciximab, eptifibatide, tirofiban, nibindi. prostaglandine EP3 reseptor inhibitor, ibice bishya bya chimique hamwe nibisohoka neza mubuvuzi gakondo bwubushinwa.
