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Mecobalamin ni ugufata ubuvuzi bwa peripheri

Ibisobanuro bigufi:

Gushonga Ingingo:> 190 ° C (Ukuboza.)

Imiterere yo kubika: Gufunga byuzuye, ububiko muri firezer munsi ya metero 20 ° C.

Gukemurwa: Dmso (gato), methanol (bike), amazi

Coeeffity Coeefficial: (PKA) PK1: 7.64 (+1) (25 ° c)

Ifishi: ikomeye

Ibara: umutuku wijimye

Amazi yonyine: gushonga igice mumazi akonje, amazi ashyushye.

Guhagarara: Ssense yoroheje


Ibisobanuro birambuye

Ibicuruzwa

Ibisobanuro birambuye

Izina  Mecobalamin
Umubare wa Cas 1342-55-4
Formulala C63H90ConC13O14P
Uburemere bwa molekile 1343.4
Gushonga > 190 ° C (Ukuboza.)
Kudashoboka Dmso (gato), methanol (bike), amazi (gato)
Ubuziranenge 99%
Ububiko Yashyizweho ikimenyetso cyumye, ububiko muri firigo, munsi ya -20 ° C.
Ifishi Bikomeye
Ibara Umutuku wijimye
Gupakira Pe Umufuka + Umufuka wa Aluminium

Synonyme

MECOBALAMIN;MECOBALAMINE;METHYLCOBALAMIN;cobalt-methylcobalamin;cobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester),;Methyl-5,6-dimethylbenzimidazolylcobalamin;Vitamin B12;Algobaz

Ingaruka ya farumasi

Imikorere ya Physiologique

Methylcobalamin ni ibiyobyabwenge byo kuvura indwara za peripheri. Ugereranije nandi vitamine B12 imyiteguro, ifite ibyiza byo guhinduranya imitsi. Irashobora guteza imbere acide-poroine-lipid metabolism binyuze muri methyl guhinduranya no gusana ibice byangiritse. Ifite uruhare rwa Coenzyme mugikorwa cyo guhuza intsinzi kuva muri Homocyste, cyane cyane yitabiriwe cyane cyane muri thymidine kuva mucleone ya dexkididine, kandi iteza imbere synthesis ya ADN na RNA. Byongeye kandi, mu igeragezwa rya selile za ruswa, ibiyobyabwenge byongera ibikorwa bya methionine synthase kandi biteza imbere synthesis ya Myelin Lipid Lecithin. Kunoza imyanda ya metabolike yingingo zifite ubwoba zirashobora guteza imbere synthesis ya axons hamwe na poroteyine zabo, kora umuvuduko wubwikorezi bwa poroteine ​​zegera ibisanzwe, kandi ukomeze imikorere ya axons. Inshinge ya methylcobalamin irashobora kandi kubuza icyifuzo kidasanzwe cyo guhinduranya imitsi, guteza imbere no kugabana na erythroblasts, no guteza imbere amaraso. Methylcobalamin arashobora kugarura vuba kubarana na selile itukura, hemoglobine, hamwe na HEMACRIT AGACIRO bwite y'imbeba zagabanutse kubera ibiyobyabwenge B12. Byakoreshejwe kuri megaloblasti ya megaloblastique ya megaloblastique na peripheri yubuvuzi bwa peripheri biterwa no kubura vitamine B12.

 

Ingaruka ya farumasi

Methylcobalamin ni ukuva kuri vitamine B12. Yitiriwe imiterere yimiti. Igomba kwitwa "methyl vitamini B12". Irashobora guteza imbere metabolism y'ibinure, gikangura synthesis ya lecithin mumiseli ya Schwann, gusana umuvuduko wangiritse, kandi utezimbere umuvuduko wo mu mitsi; Irashobora kwinjiza mu buryo butaziguye no gukangurira kuvugurura amato yangiritse; Kangura synthesis ya poroteyine yingirabuzimafatizo, komeza ANABOLISm, irinde kwangirika kwa axon; kwitabira synthesis ya acide nucleic, jya imbere imikorere ya Bematopoitic. Ubuvuzi, akenshi bikoreshwa mugufata ibya diyabete neuropathique, kandi gukoresha igihe kirekire nabyo bigira ingaruka runaka kubibazo byimigezi manini ya maraso muri diyabete. Methylcobalamin ikoreshwa cyane cyane ku ndwara za peripheri zatewe na diyabete na anemia ya megaloblastike yatewe no kubura vitamine B12. Birakoreshwa cyane mubuvuzi hamwe ningaruka nkeya.

 

Imikoreshereze
Ikoreshwa mu kuvura indwara za sisitemu ya sisitemu yo guhagarika umutima, kugabanya ububabare no kunanirwa, kugabanya vuba Nealing

 

 


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