GH / IGF-1 igabanya physiologique ifite imyaka, kandi izi mpinduka ziherekejwe numunaniro, imitsi ya atrophy, yongereye ashimangira tissue, no kwangirika kwumva ...
Mu 1990, Rudman yashyize impapuro mu kinyamakuru gishya cy'Ubwongereza cyatunguye umuryango w'ubuvuzi - "gukoresha imisemburo yo gukura kw'abantu mu bantu barengeje imyaka 60". Rudman yatoranije abagabo 12 bafite imyaka 61-81 kubigeragezo byubuvuzi:
Nyuma y'amezi 6 yo gutera inshinge za HGH, ingingo zari zifite impuzandengo yo ku mwanya wa 8.8% mu mitsi y'imitsi, 14.4% mu ruhu rwakozwe n'amagufwa, 1% mu cyuho na 17% ugereranije n'itsinda rishinzwe kugenzura imyaka ingana. %, byanzuye ko impinduka enye mu ngingo zose zari bato ku myaka 10 kugeza kuri 20.
Uyu mwanzuro watumye abantu benshi batezimbere imisemburo yo gukura kwabantu (RHGH) nkibiyobyabwenge byo kurwanya gusa, kandi nintandaro yibyo abantu benshi bizera ko inshinge za RHGH zishobora kurwanya. Kuva icyo gihe, abatwara amabati benshi bakoresheje HGH nk'ibiyobyabwenge byo kurwanya imyaka, nubwo bitemewe na FDA.
Icyakora, nk'ubushakashatsi bukomeje kwiyongera, abahanga mu bya siyansi basanze inyungu nto ku mubiri wo kongera ibikorwa bya GH / IGF-1 AXIS ntabwo ari ingaruka zubuzima, ahubwo ni ingaruka zubuzima:
Imbeba zirenze GH ni nini, ariko zifite 30% -40% igihe gito cyoroheje kuruta imbeba zayo zo mu gasozi [2], hamwe n'impinduka za moduphologiya (GlomeKologiste (GlomeKulogisi binini) na insuline.
Urwego rwo hejuru rwa GH rutera imigezi, amagufwa, n'ingingo zimbere, biganisha kuri gihamya (mubana) na Acromegaly (mubantu bakuru). Abakuze bafite gh barenze urugero bakunze kuba ifitanye na diyabete n'ibibazo by'umutima, ndetse no guhura na kanseri.
Igihe cya nyuma: Jul-22-2022