RU-58841 Ikoreshwa nkukwirinda umusatsi no kogosha kwumugabo
Ibicuruzwa birambuye
| Izina | RU-58841 |
| Numero ya CAS | 154992-24-2 |
| Inzira ya molekulari | C17H18F3N3O3 |
| Uburemere bwa molekile | 369.34 |
| Umubare wa EINECS | 1592732-453-0 |
| Ingingo | 493.6 ± 55.0 ° C (Biteganijwe) |
| Ubucucike | 1.39 |
| Imiterere y'ububiko | Ikidodo cyumye, Ubike muri firigo, munsi ya -20 ° C. |
| Ifishi | Ifu |
| Ibara | Cyera |
| Gupakira | Umufuka wa PE + Aluminium |
Synonyme
RU58841; 4- (4,4-Dimethyl-2,5-dioxo-3- (4-hydroxybutyl) 1-imidazolidinyl) -2- (trifluoromethyl) benzonitrile; 4- [3- onitrile; 4- [3- (4-Hydroxybutyl) -4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl] -2- (trifluoroMethyl) ben zonitrile; RU-58841E: candyli (kuri) umuvuduko mwinshi (akadomo) com; CS-637; RU588841; RU58841; RU58841; RU-58841
Ingaruka ya Farumasi
Ibisobanuro
RU 58841 (PSK-3841) ni antrogene reseptor antagonist iteza imbere umusatsi.RU58841 ni umuti wiperereza wakozwe kugirango uvurwe na alopeciya ya andorogène, izwi kandi ko ari umusatsi wumugabo (MPD).
Nka anti-androgene yibanze, ihame ryibikorwa ntabwo ari kimwe na finasteride. Finasteride ikora kuri 5α reductase, ibuza ihinduka rya testosterone muri DHT, kandi igabanya ibiri muri DHT mumubiri. RU58841 ihagarika imikoranire hagati ya dihydrotestosterone niyakirwa ryimisatsi, ntabwo igabanya mu buryo butaziguye ibirimo DHT, ariko igabanya guhuza imiyoboro ya DHT hamwe n’imisatsi y’imisatsi, kugirango igere ku ntego yo kuvura alopeciya.
4- [3- (4-Hydroxybutyl) -4,4-dimethyl-2.5Niba 4- [3-.Mugihe uhuye nuruhu, kura imyenda yanduye, kwoza uruhu neza ukoresheje isabune namazi, hanyuma ushakire kwa muganga mugihe habaye ikibazo;
Ingaruka Kuruhande
RU58841 ikoreshwa kumutwe, yinjizwa nu musatsi, kandi mubyukuri, irashobora kwinjira mumaraso kandi ikagira ingaruka kubindi bice byumubiri. Ariko nta ngaruka zifatika zabonetse mubushakashatsi bwibikorwa byinguge. Nyamara, abantu bamwe bagerageje RU58841 bavuga ko bahuye ningaruka zishobora guterwa no gukoresha RU, harimo kurakara kuruhu, kugabanuka kwa libido, kudakora neza, isesemi, amaso atukura, umutwe, no kubabara umutwe.
