Vancomycine ni antibiyotike ya glycopeptide ikoreshwa muri antibacterial
Ibisobanuro birambuye
| Izina | Vancomycin |
| Numero ya CAS | 1404-90-6 |
| Inzira ya molekulari | C66H75Cl2N9O24 |
| Uburemere bwa molekile | 1449.25 |
| Umubare wa EINECS | 215-772-6 |
| Ubucucike | 1.2882 (igereranya) |
| Ironderero | 1.7350 (igereranya) |
| Imiterere yo kubika | Ikidodo cyumye, 2-8 ° C. |
Synonyme
Vancomycin (baseand / orunspecifiedsalts); VANCOMYCIN; VancomycinBase; (3S, 6R, 7R, 22R, 23S, 26S, 36R, 38aR) -3- (2-Amino-2-oxoethyl) -44 - [ 3-amino-2,3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl) -β-D-glucopyranosyl] oxy] -10,19-dichloro-2,3,4,5, 6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6 - [[(2R) -4-meth ) -1-oxopentyl] amino] -2,5,24,38,39-pentaoxo-22H-8,11: 18,21-Dietheno-23,36- (iminomethano) -13,16: 31,35-dimetheno -1H, 16H- [1,6,9] oxadiazacyclohexadecino [4,5-m]
Ibisobanuro
Vancomycine ni antibiyotike ya glycopeptide.Uburyo bwibikorwa byabwo ni uguhuza cyane na alanylalanine kumpera ya poly-terminal ya preursor peptide yurukuta rwa bagiteri yoroheje, ikabuza synthesis ya macromolecular peptidoglycan igizwe nurukuta rwa bagiteri, bikaviramo Kurimbuka kwakagari. urukuta rwica bagiteri.Vancomycine ifite akamaro kanini kwandura indwara ziterwa na Gram-positif, cyane cyane izatewe na methicilline irwanya Staphylococcus aureus, epidermidis ya Staphylococcus, na Enterococcus irwanya izindi antibiyotike cyangwa zifite ingaruka mbi.
Ibyerekana
Iragarukira gusa ku kwandura sisitemu iterwa na methicilline irwanya Staphylococcus aureus (MRSA) n'indwara zo mu nda n'indwara zanduye ziterwa na Clostridium difficile;abarwayi ba penisiline-allergique ntibashobora gukoresha penisiline cyangwa cephalosporine kubarwayi banduye staphylococcal, cyangwa abafite ubwandu bukabije bwa staphylococcal bananiwe kwitabira antibiyotike yavuzwe haruguru, vancomycine irashobora gukoreshwa.Iki gicuruzwa nacyo gikoreshwa mu kuvura Enterococcus endocarditis na Corynebacterium (Diphtheria-isa) endocarditis mu bantu allergique kuri penisiline.Kuvura indwara ya staphylococcus iterwa na arteriovenous shunt kwandura abarwayi ba hemodialysis allergic kuri penisiline na allergic kuri penisiline.
