Daptomycin 103060-53-3 kubibazo byandura
Ibisobanuro birambuye
| Izina | Daptomycin |
| Umubare wa Cas | 103060-53-33-3 |
| Formulala | C72H1017O26 |
| Uburemere bwa molekile | 1620.67 |
| Umubare wa EINECS | 600-389-2 |
| Gushonga | 202-204 ° C. |
| Ingingo itetse | 2078.2 ± 65.0 ° C (Byumvikane) |
| Ubucucike | 1.45 ± 0.1 g / cm3 (byahanuwe) |
| Flash point | 87 ℃ |
| Imiterere | Yashyizweho ikimenyetso cyumye, ububiko muri firigo, munsi ya -20 ° C. |
| Kudashoboka | Methanol: LOCK5MG / ML |
| Coeffity | (PKA) 4.00 ± 0.10 (byahanuwe) |
| Ifishi | ifu |
| Ibara | ibara ritagira ibara ry'umuhondo |
Synonyme
N- (n-- ; N-- Ecyl) -L-Tryptophyl-D-Asparaginyl-l-aspartyl-l-ornithyl-l-ornithyl-l-ASHITHYLLLGLYL-D-ALOMLLLGLYLGLYL-D-SORYL-L-3R-NOTHYL-L-α- glutamyl-α, 2-diamino-γ-Oxo-bezenebunoikaCacid (13-4); Daptomycine; Daptomycin, Daptomycin
Ibisobanuro
Umuseke wa antibiyotike ni antibioptide ya cyclic hamwe ninzego nshya yakuwe mu muhogo wa fermetttomces Guhindura imitungo ya Cytoplasmic Membranes irashobora guhungabanya imikorere ya bagiteri muburyo bwinshi kandi yica byihuse kandi yica bagiteri nziza. Usibye ubushobozi bwo gukora kuri bagiteri nziza cyane ya bagiteri-mwiza cyane, DaptoMycin ni ngombwa mu miterere yitaruye yerekanye kurwanya Methicillin, VancomyCin, na Liconolid muri Vitro. Ifite ibikorwa bikomeye, kandi uyu mutungo ufite ingaruka zikomeye zubuvuzi kubarwayi barwaye cyane. Umusonga wa EosinoMonic ni indwara idasanzwe kandi ikomeye cyane hamwe n'ibimenyetso birimo umuriro, inkorora, kubura guhumeka, no guhumeka.
Ingaruka ya Antibacterial
DaptoMycin afite ibikorwa byiza bya bagiteri kuri bagiteri zitandukanye za antibiyotike zinyuranye za antibiyotike, nka mic = 0.06-0-0. Mic = 0.0625 ~ 1μg / ml kuri bagiteri, mic = 0.12 ~ 0.5μG 0.5 ~ 1μG / ML, na Mic ya Encococcus irwanya Glycopeptide antibiyotique ni 1 ~ 2μ / ml.
