Teriparatide Acetate API ya Osteoporose CAS NO.52232-67-4

Teriparatide irashobora guhuza metabolisme yamagufwa muguhagarika osteoblast apoptose, gukora ingirabuzimafatizo zamagufwa, no kongera itandukaniro rya osteoblast. Rimwe na rimwe itera reseptor ya PHT-I hejuru ya osteoblasts, ingirangingo zifata amagufwa hamwe na selile marrow stromal stem selile igenga adenylate cyclase-cyclic adenosine monophosphate-protein kinase Inzira yo guteza imbere itandukaniro rya osteoblast no kuramba kwa osteogenezi; Bikwirakwiza ikwirakwizwa ryimirongo ya osteoblast ikoresheje fosifate C-cytoplasmic calcium-protein Chemical Book kinase C yerekana inzira; Muguhagarika ibikorwa bya transactivation ya PPARγ, bigabanya gutandukanya ingirabuzimafatizo ya tromal kumurongo wa adipocyte kandi byongera umubare wa osteoblasts; Kugenzura mu buryo butaziguye imikurire yamagufwa muguhindura cytokine, kurugero, iGF-1 irashobora gushishikarizwa guhuza osteoblasts, bityo igatera amagufwa;

Inzira yo gukora amagufwa igengwa na Wnt yerekana inzira, bityo bikongera amagufwa.