Atosiban Acetate Used for Anti Premature Birth Featured Image

Atosiban Acetate Yifashishijwe Kurwanya Kubyara

Ibisobanuro bigufi:

Izina: Atosiban

Numero ya CAS: 90779-69-4

Inzira ya molekulari: C43H67N11O12S2

Uburemere bwa molekuline: 994.19

EINECS Numero: 806-815-5

Ingingo yo guteka: 1469.0 ± 65.0 ° C (Biteganijwe)

Ubucucike: 1.254 ± 0.06 g / cm3 (Biteganijwe)

Imiterere yo kubika: -20 ° C.

Gukemura: H2O: ≤100 mg / mL

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Ibisobanuro birambuye

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Ibisobanuro birambuye

Izina	Atosiban
Numero ya CAS	90779-69-4
Inzira ya molekulari	C43H67N11O12S2
Uburemere bwa molekile	994.19
Umubare wa EINECS	806-815-5
Ingingo yo guteka	1469.0 ± 65.0 ° C (Biteganijwe)
Ubucucike	1.254 ± 0.06 g / cm3 (Biteganijwe)
Imiterere yo kubika	-20 ° C.
Gukemura	H2O: ≤100 mg / mL

Ibisobanuro

Atosiban acetate ni disulfide ihujwe na cyclic polypeptide igizwe na acide 9 amine.Ni molekile ya oxytocine ihinduwe kumwanya wa 1, 2, 4 na 8. N-terminus ya peptide ni aside-mercaptopropionic aside (thiol hamwe na sulfhydryl groupe ya [Cys] 6 ikora umurunga wa disulfide), C-terminal ni muburyo bwa amide, aside amine ya kabiri kuri N-terminal ni Ethylated yahinduwe [D-Tyr (Et)] 2, kandi acetate ya atosiban ikoreshwa mumiti nka vinegere ibaho muburyo bwumunyu wa aside, mubisanzwe uzwi nka atosiban acetate.

Gusaba

Atosiban ni oxytocine na vasopressine V1A ikomatanya reseptor antagonist, reseptor ya oxytocine isa muburyo bwa vasopressine V1A.Iyo reseptor ya oxytocine ihagaritswe, oxytocine irashobora gukora binyuze muri reseptor ya V1A, bityo rero birakenewe ko uhagarika inzira ebyiri za reseptor icyarimwe, kandi antagonism imwe ya reseptor imwe irashobora kubuza kugabanuka kwa nyababyeyi.Iyi nayo ni imwe mu mpamvu zingenzi zituma β-reseptor agoniste, calcium umuyoboro wa calcium na prostaglandin synthase inhibitor idashobora kubuza neza kwikuramo nyababyeyi.

Ingaruka

Atosiban ni reseptor antagonist ya oxytocine na vasopressine V1A, imiterere yimiti isa na byombi, kandi ifite aho ihurira na reseptor, kandi irushanwa na oxytocine na vasopressine V1A, bityo bikabuza inzira y'ibikorwa bya oxytocine na vasopressine no kugabanya kugabanuka kwa nyababyeyi.

Mbere: Teriparatide Acetate API ya Osteoporose CAS NO.52232-67-4

Ibikurikira: Carbetocine kugirango wirinde kwandura kwa nyababyeyi no kuva amaraso nyuma yo kubyara

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