Atosiban acetate ikoreshwa muguturika imburagihe
Ibisobanuro birambuye
| Izina | Atosiban |
| Umubare wa Cas | 90779-49-4 |
| Formulala | C43H67n11O12S2 |
| Uburemere bwa molekile | 994.19 |
| Umubare wa EINECS | 806-815-5 |
| Ingingo itetse | 1469.0 ± 65.0 ° C (Byahanuwe) |
| Ubucucike | 1.254 ± 0.06 g / cm3 (byahanuwe) |
| Imiterere | -20 ° C. |
| Kudashoboka | H2O: ≤100 MG / ML |
Ibisobanuro
Atosiban acetate ni udukoko twclic polyplipde igizwe na aside 9 amino. Ni molekile yahinduwe kuri molekile kumwanya wa 1, 2, 4 na 8. N-termide ya peptide 3-merchydry), aside ya merfhydry niyide .
Gusaba
Atosiban ni oxytocin na vasopressin v1a yahujije reseptor antagor, reseptor oxytocin isa na vasworsin v1a reseptor. Iyo oxytocin yakiriye, oxytocin irashobora gukora binyuze muri reseptor ya V1, bityo birakenewe kugirango uhagarike inzira ebyiri zakiriye icyarimwe, kandi kuntana na ontagonism imwe ya reseptor imwe irashobora kubuza gutandukana. Iyi kandi ni imwe mumpamvu nyamukuru zituma β-kwakira abarozi, abatsinze Calcium na Prostaglandin synthase yububiko bwa prostaglanin idashobora kubuza neza imico yinda.
Ingaruka
Atosiban ni antagoporo ya oxytocine ya oxytocine na vasopressin v1a, imiterere yacyo irasa na kabiri, kandi ifite itandukaniro rya oxytocin na vasopressin na vasopressin no kugabanya imiterere ya nyababyeyi.
