Ganelix acetate peptide api
Ibisobanuro birambuye
| Izina | Ganyirelix Acetate |
| Umubare wa Cas | 123246-29-7 |
| Formulala | C80H113CLN18O13 |
| Uburemere bwa molekile | 1570.34 |
Synonyme
AC-DNPA-DPAL-Ser-Ser-Dhar (et2) -Ro-Har (Ganyirelixum; Ganyirelix acetate; Ganyirelix; Ganyirelix acetate USP / EP /
Ibisobanuro
Ganyirelix ni ikigo cya syntheptide decapeptide, numunyu wacyo wa acetate, ganirelix acetate ni umuswa wa gonadopropin-kurekura gnadotropin-gusohora gnrh) kwakira antagonositiste. Acide acide acide ni: AC-D-2Npa-D-3Pal-Ser-Homoarg (9,10 - et2) -Po-NH2. Ahanini, ikoreshwa mu bagore barimo gukorana tekinoroji y'imyororokere ya Ovariyeri yagenzuwe kuri futmore imburagihe no kuvura indwara z'uburumbuke kubera iyi mpamvu kubera iyi mpamvu. Ibiyobyabwenge bifite ibiranga ibintu bidafite ishingiro, urugero rwo gutwita rurerure hamwe nigihe gito cyo kuvura, kandi gifite ibyiza ugereranije nibiyobyabwenge nkibi.
Ibikorwa bya farumasi
Ikibuga cya pulsatile cya Gonalmone-kurekura imisemburo (GNRH) itera synthesis no gusohora lh na fsh. Inshuro ya LH Pulsex hagati kandi yatinze ibyiciro bya hafi ni 1 kumasaha. Izi mpipo zigaragarira mumyanda yinziba muri Serum Lh. Mugihe cyo hagati yimyaka, irekurwa ryinshi rya GNRH ritera kwiyongera lh. Umuryango wo hagati lh Surge arashobora gutera ibisubizo byinshi bya physiologique, harimo: ovulation, oocyte meiotic gusubukurwa, hamwe na corpus luteum. Imiterere ya corpus luteum itera urwego rwa Serum Progesterone kuzamuka, mugihe urwego rwa Estradiol rugwa. Ganyirelix acetate ni gnrh antagonist irushanwa irushanwa rya gnrh Resptors kuri Pitoitary Gonal Itanga imbaraga, zishingiye ku buryo bwa gonadotropin. Ingaruka ya Kibireory ya Ganyalix Acetate kuri Pituitary LH imbaraga zari zikomeye kuruta iyo kuri fsh. Ganyirelix Acetate yananiwe gutera imbere irekurwa rya mbere Gonadotropines, ihuye na antagonism. Urwego rwa Pituitary LH na Fsh rwabaye mu masaha 48 nyuma ya Ganirelix Acetate yarahagaritswe.
