Carbetocine kugirango irinde kugabanuka kwa nyababyeyi hamwe na postpartatum hemorrhage
Ibisobanuro birambuye
| Izina | Carbetocine |
| Umubare wa Cas | 37025-55-1 |
| Formulala | C45h69n11O12s |
| Uburemere bwa molekile | 988.17 |
| Umubare wa EINECS | 253-31-6 |
| Kuzunguruka | D -69.0 ° (C = 0.25 muri 1m acide) |
| Ingingo itetse | 1477.9 ± 65.0 ° C (byahanuwe) |
| Ubucucike | 1.218 ± 0.06 g / cm3 (byahanuwe) |
| Imiterere | -15 ° C. |
| Ifishi | ifu |
Synonyme
Butyryl-Tyr (Me) -Ibisobanuro-gln-asn-cys-ps-leu-gly-nh2, Butyryl-Tyr (Njye) -igihe-gln-asn-cys-ps-leu-gly-nh2trifLuororotacetacetacetantalt; . (Butyryl1, Tyr (Njye) 2) - ibikoresho byanyuma; . Carbetocine; CarbetocintriFiroTacetalt; (2-O-methyltyrostine) -D-Amino-1-Carbaoxytocin
Ibinyabuzima
Carbetocin, oxytocine (ott) analog, ni oxytocin reseptor agonist hamwe na ki ya 7.1 nm. Carbetocine ifite ubuhinzi burebure (ki = 1.17 μm) kuri chimeric n-termis ya oxytocine reseptor. Carbetocin ifite ubushobozi bwo guhagarika postpartage. Carbetocin irashobora kwinjira kuri bariyeri y'amaraso kandi ifite ibikorwa bikunda intide
Imikorere
Carbetocine ni oxtthecin yohejuru-gukora kuri oxytocin 8-peptide analote hamwe numutungo wa Abunist, hamwe numutungo wacyo nibikoresho bya farumasi bisa na oxytocine ya oxytocine. Kimwe na oxytocine, Carbetocin ihuza kwakirwa imitsi yo mu mitsi yo mu mitsi ya tebani, bigatera imigezi ya nyababyeyi, bitera inzitizi ya nyababyeyi, yongera injyana ya nyababyeyi, yongera injyana ya nyababyeyi, yongera injyana ya nyababyeyi, yongera injyana ya nyababyeyi, yongera injyana ya nyababyeyi, yongera injyana ya nyababyeyi, yongera injyana ya nyababyeyi, yongera inshuro nyinshi kandi yongera ijwi rya nyababyeyi no kongera ijwi rya nyababyeyi hashingiwe ku kwikuramo umwimerere. Urwego rwa Oxytocin rwakira muri nyababyeyi ari hasi mu bihugu bitatwite, kwiyongera mugihe cyo gutwita, no ku mpinga mugihe cyarimo. Kubwibyo, Carbetocin nta ngaruka igira kuri nyababyeyi udatwite, ariko ifite ingaruka zikomeye nyabagendwa nyababyeyi ntwite na nyabage nshya.
Guhindura Igenzura
Impinduka zigenzurwa ukurikije inzira. Ukurikije ingaruka ningaruka nuburemere, impinduka zishyirwa mubikorwa nkuru nkuru nkururubuga. Guhindura Urubuga bifite ingaruka nke kumutekano nubwiza bwibicuruzwa, bityo ntibikeneye kwemezwa no kumenyeshwa abakiriya; Impinduka nto zifite ingaruka ziciriritse kumutekano nubwiza bwibicuruzwa, kandi ukeneye kumenyesha umukiriya; Impinduka zikomeye zifite ingaruka nyinshi kumutekano nubwiza bwibicuruzwa, kandi bikeneye kwemezwa numukiriya.
Ukurikije inzira, guhindura kugenzura bitangirana no guhindura impinduka muburyo bwo guhindura ibisobanuro kandi byumvikana impinduka zasobanuwe. Isuzuma noneho rigizwe nyuma yo gusaba, bikorwa no guhindura kugenzura amashami. Hagati aho, kugenzura impinduka zishyizwe mu rwego rwingenzi, urwego rusange nurugingo ruto. Nyuma yo gusuzuma neza kimwe nicyiciro, urwego rwose rwo guhindura rugomba kwemezwa numuyobozi wa QA. Igenzura ryimpinduka zikorwa nyuma yo kwemezwa hakurikijwe gahunda y'ibikorwa. Igenzura ryahinduwe rirangiye nyuma yuko Qa yemeza ko kugenzura impinduka byashyizwe mubikorwa neza. Niba birimo kumenyesha abakiriya, umukiriya agomba kumenyeshwa mugihe nyuma yo kugenzura byemewe
