Desmopressine Acetate yo kuvura Diyabete yo hagati Insipidus
Ibicuruzwa birambuye
| Izina | Desmopressin |
| Numero ya CAS | 16679-58-6 |
| Inzira ya molekulari | C46H64N14O12S2 |
| Uburemere bwa molekile | 1069.22 |
| Umubare wa EINECS | 240-726-7 |
| Kuzenguruka byihariye | D25 +85.5 ± 2 ° (ubarwa kuri peptide yubusa) |
| Ubucucike | 1.56 ± 0.1 g / cm3 (Biteganijwe) |
| RTECS No. | YW9000000 |
| Imiterere yo kubika | Ubike kuri 0 ° C. |
| Gukemura | H2O: gushonga20mg / mL, bisobanutse, bitagira ibara |
| Coefficient ya acide | (pKa) 9.90 ± 0.15 (Biteganijwe) |
Synonyme
MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2; MINIRIN; [DEAMINO1, DARG8] VASOPRESSIN; [DEAMINO-CYS1, D-ARG8] -VASOPRESSIN; DDAVP, UMUNTU; DESMOPRESSIN; DESMOPRESSIN, UMUNTU; DESAMINO- [D-ARG8] VASOPRESSIN
Ibyerekana
(1) Kuvura diyabete yo hagati insipidus. Nyuma yuko imiti ishobora kugabanya gusohoka kwinkari, kugabanya inshuro zinkari no kugabanya nocturia.
(2) Kuvura enuresis nijoro (abarwayi bafite imyaka 5 cyangwa irenga).
(3) Gerageza imikorere yinkari zimpyiko, hanyuma ukore isuzuma ritandukanye ryimikorere yimpyiko.
(4) Kuri hémofilia nizindi ndwara ziva amaraso, iki gicuruzwa kirashobora kugabanya igihe cyo kuva no kwirinda kuva amaraso. Irashobora kugabanya urugero rwo gutakaza amaraso munda no gukorerwa opozisiyo; cyane cyane ifatanije numuvuduko ukabije wamaraso mugihe cyo kubagwa, irashobora kugabanya kuva amaraso mumikorere itandukanye, kandi bikagabanya oozing nyuma yibikorwa, bishobora kugira uruhare runini mukurinda amaraso.
Kuvura diyabete insipidus
Indwara ya diyabete ni indwara ya metabolisme y'amazi irangwa no gusohora inkari nyinshi, polydipsia, hypoosmolarity, na hypernatremia. Kubura igice cyangwa byuzuye bya vasopressine (diabete yo hagati ya diabete insipidus), cyangwa kubura impyiko za vasopressine (diabete ya neprogène diabete insipidus) irashobora gutangira. Mubuvuzi, diyabete insipidus isa na polydipsia yibanze, imiterere aho gufata amazi menshi biterwa no kudakora neza muburyo bwo kugenzura cyangwa inyota idasanzwe. Bitandukanye na polydipsia y'ibanze, kwiyongera kw'amazi ku barwayi barwaye diyabete insipidus ni igisubizo kijyanye n'imihindagurikire y'umuvuduko wa osmotic cyangwa ubwinshi bw'amaraso.
