Izina | Linanlotide |
Umubare wa Cas | 85119-99- |
Formulala | C59H79N15O21S6 |
Uburemere bwa molekile | 1526.74 |
Linacllotide; LINACLITIDE; LINAELITIDEACET; LINAELITIDE; Cy-l-tyspessin; l-cystesinel-l-glutamyl-l-tlutamyl-l-tlutamyl-l-tlutamyl-l-tlutamyl -
LINACLITIDE, INGINGO YO GUKURIKIRA ADID 14, bifitanye isano n'umuryango wa Guanasine wa Guanasine Peptade kandi nicyo gipimo cyonyine cya FDA-C.) Igiti cya Agositike cyo kuvura syndromekwa
LINACLITIDE niyera kuri ifu ya Amorfous; gushonga gato mumazi na Sodium ya Sodium ya Sodium ya Sodiimi (0.9%).
LINACLITIDE Cyclase-C Kwakira Agopor Agonist (GCCA) hamwe nibikorwa byo kureba no gukoraho kandi ibikorwa bya endocrine. Kurenzallotide ndetse na metabolite irashobora guhambira kuri gaclase ya konlase-c (gc-c) kwakira hejuru yindege ya epithelium ntoya. Muburyo bwinyamanswa, linaclotide igabanya ububabare bwo kureba kandi yongerera inzira ya gastrointestinal binyuze mu gukora gc-c, no mubantu, ibiyobyabwenge byongera inzira ya coronic. Igisubizo cyibikorwa bya GC-C byiyongereyeho CGMPS yaka kandi itemewe (Cyclic Guanosine Monophoshare). CGMPS CEMPD irashobora kugabanya ibikorwa byububabare fibre no kugabanya ububabare bwo kureba mumatungo yicyitegererezo. Intracellular CGMP irashobora kongera ibanga rya chloride na Bicarbonate mumara mato mugukora CFTR (fibrosis ya transmembrane reductor,, amaherezo ikaba igana kubyutsa amazi mato no kwimura amara mato.
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